Title Multicompartment polymersome gel for encapsulation
نویسندگان
چکیده
منابع مشابه
Multicompartment polymersome gel for encapsulation
We introduce an approach that combines the concepts of emulsiontemplating and dewetting for fabricating polymersomes with a large number of compartments. The resultant polymersome gel behaves as a gel-like solid, but is a true vesicle suspended in an aqueous environment. Due to the thin membranes that separate the compartments, the polymersome gels have a high volume fraction of internal phase ...
متن کاملIn addition, the structure of the voids in conventional polyHIPEs are usually spherical; the low packing density of spherical droplets can limit the volume fraction of the polyHIPEs. Polymersomes with compartments separated by thin walls of copolymers
Abtract We introduce an approach that combines the concepts of emulsion-templating and dewetting for fabricating polymersomes with a large number of compartments. The resultant polymersome gel behaves as a gel-like solid, but is a true vesicle suspended in an aqueous environment. Due to the thin membranes that separate the compartments, the polymersome gels have a high volume fraction of intern...
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Polymersomes are vesicles which consist of compartments surrounded by membrane walls that are composed of lamellae of block copolymers. They are important for numerous applications in encapsulation and delivery of active ingredients such as food additives, drugs, fragrances, and enzymes. Polymersomes are typically prepared by precipitating block copolymers from their solvents through addition o...
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The field of therapeutics is evolving to include a greater proportion of higher molecular weight, hydrophilic biological compounds. To cater for this new era in healthcare the concomitant development of appropriate drug delivery systems is essential to aid cellular permeation. In this manuscript we present the synthesis, characterisation and biological evaluation of a charge neutral polymersome...
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The encapsulation of chloroperoxidase from Caldariomyces fumago (CPO) in block copolymer polymersomes is reported. Fluorescence and electron microscopy show that when the encapsulating conditions favour self-assembly of the block copolymer, the enzyme is incorporated with concentrations that are 50 times higher than the enzyme concentration before encapsulation. The oxidation of two substrates ...
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